Sour Kangaroo

Sour Kangaroo is the main antagonist in Horton Hears a Who (2008). However, she reforms in the end.

She plays Queen Chrysalis in My Little Animal: Friendship Is Magic
She is a changeling queen.

She plays Maleficent in Sleeping Tigress
She is an evil witch.

She plays the Matchmaker in Gialan
She is a Matchmaker.

She plays Auntie Shrew in The Secret of NIMH (Nuclearzeon Animal Style)
She is a shrew.